Dinutuximab Biosimilar - Research Grade

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SKU
ICH5308
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$315.00 - $19,890.00

Dinutuximab Biosimilar - Research Grade

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Species Reactivity
Human
Target
Ganglioside GD2
Concentration
5mg/ml
Isotype
Human IgG1 Kappa
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Shipping Conditions
Blue ice
Background
Disialoganglioside GD2 is a glycolipid antigen highly expressed on neuroectodermal tumours and a prominent target in neuroblastoma and immuno-oncology research. Our research-grade anti-GD2 recombinant monoclonal antibody is an unconjugated, non-therapeutic analog of dinutuximab for research use only. Manufactured to in vivo standards with a low-endotoxin formulation, it is available in scalable milligram (mg) to gram (g) quantities for bulk and high-throughput laboratories. It performs consistently as a control and active reagent in ganglioside-binding assays, in vitro functional screening, ADCC and CDC studies, and in vivo tumour models.
Other Names
14.18,ch14.18,MAb-14.18,MOAB Ch14.18,ganglioside GD2 (disialoganglioside GD2)
Specificity
Detects human Ganglioside GD2
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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