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Oregovomab Vedotin Biosimilar - Research Grade
$714.00 - $3,085.00
Oregovomab Vedotin Biosimilar - Research Grade
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
CA125 / MUC16
Concentration
1mg/ml
Isotype
IgG1
Host
CHO Cells
Uniprot
Q8WXI7
Shipping Conditions
Room Temp
Background
CA125/MUC16 is a tumor-associated mucin widely investigated as a target for ovarian-cancer therapeutics and antibody-drug conjugates. This research-grade human IgG1 antibody is an unconjugated, non-therapeutic analog of oregovomab vedotin, produced in CHO cells against CA125/MUC16. Provided for research use only, it is formulated to low endotoxin for in vivo compatibility and manufactured in scalable milligram (mg) to gram (g) quantities for bulk and high-throughput laboratories. As the naked antibody backbone of a vedotin-class conjugate, it is especially useful for ADC payload-linker development, internalization studies, functional binding assays, and preclinical tumor-targeting models.
Other Names
MMAE
Formulation
25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Delivery Time
1 week
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