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Cobolimab Biosimilar - Research Grade
$710.00 - $6,900.00
Cobolimab Biosimilar - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
HAVCR2ï؟½
Concentration
5mg/ml
Isotype
IgG4 - kappa
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
Q8TDQ0
Shipping Conditions
Blue ice
Background
HAVCR2 (TIM-3) is an inhibitory receptor on exhausted T cells and innate immune cells that dampens antitumor responses, a prominent target in immuno-oncology research. This reagent is an unconjugated, non-therapeutic analog of cobolimab, a human IgG4-kappa recombinant antibody supplied for research use only (RUO). It is an ultra-pure, low-endotoxin preparation built to in vivo standards and produced in scalable milligram-to-gram quantities for high-throughput laboratories. It supports checkpoint functional assays, T-cell exhaustion studies, in vitro screening and preclinical tumor-immunology models examining TIM-3 biology. The ultra-pure, low-endotoxin material is offered at milligram-to-gram scale, giving high-throughput labs consistent performance across every lot.
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Delivery Time
3-4 weeks
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