Bulk Anti-Human HLA-DP (B7/21) Antibody

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SKU

ICH1024

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$400.00

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Bulk anti-human HLA-DP antibody (B7/21) [ICH1024]

More Information
Product Specific Citations	Saggau, Carina et al. Autoantigen-specific CD4+ T cells acquire an exhausted phenotype and persist in human antigen-specific autoimmune diseases. Immunity, Volume 57, Issue 10, 2416 - 2432.e8
Species Reactivity	Human
Target	HLA-DP
Concentration	1.0 mg/ml
Isotype	Mouse IgG3
Host	Mouse
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Application Notes	Each investigator should determine their own optimal working dilution for specific applications.
Applications	Western Blot, Immunocytochemistry, Flow Cytometry
Storage	anti-HLA-DP In Vivo Antibody - Low Endotoxin (B7/21) is stable for at least six (6) weeks when stored at 2-8°C. For long-term storage, aliquot in working volumes without diluting and store at ≤ 20°C in a manual defrost freezer. Avoid Repeated Freeze
Endotoxin	≤ 1.0 EU/mg as determined by the LAL method
Purity	>95% by SDS-PAGE and HPLC
Formulation	No carrier proteins or preservatives added in 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4.
Purification Method	This monoclonal antibody was purified using Protein A
Specificity	Anti-HLA-DP In Vivo Antibody - Low Endotoxin (B7/21) recognizes a (Mr 26-34 kDa) class II major histocompatibility complex (MHC) antigen. The antibody recognizes a monomorphic determinant present on cells expressing DP1, DP2, DP3, DP4 and DP5.
Shipping Conditions	Blue ice
Other names	HLA-DP Monomorphic
clone	B7/21
Buffer	ICH3001-100ml ICH3002-100ml ICH3003-100ml
Antigen Distribution	The HLA-DP antigen is present on approximately 10% of normal peripheral blood lymphocytes but not on resting peripheral T-lymphocytes. HLA-DP is present in low density on peripheral blood monocytes and mitogen-stimulated T-lymphoblasts. Anti-HLA-DP reacts
Immunogen	Unknown
Aggregation	Aggregation level ≤ 5%

Product Highlights:

This antibody is a mouse IgG3 and is prone to precipitation at lower temperatures (2-8, -70C) resulting in a slight opaque white liquid. If you allow the antibody to come back to room temperature, the majority of the precipitate will re-solubilize. We would still recommend a centrifugation/filtration as there could still be a small amount of precipitated material. ichorbio's bulk anti-human HLA-DP Antibody (B7/21) [ICH1024] is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility.

Isotype Control:

Mouse IgG3 Isotype Control for In Vivo - Low Endotoxin [MG3-35] (ICH2249)

Alternative Names: