Back to Top
Denosumab Biosimilar - Research Grade
Add recommended extras
Bulk Denosumab Biosimilar - Research Grade
| Product Specific Citations |
RANKL neutralisation prevents osteoclast activation in a human in vitro ameloblastoma-bone model Pape et al. RANKL neutralisation prevents osteoclast activation in a human in vitro ameloblastoma-bone model. Journal of Tissue Engineering (2022).
|
|---|---|
| Concentration | 1.0 - 5.0 mg/ml |
| Isotype | Human IgG2 |
| Host | Humanized |
| Use | Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
| Storage | Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at ï؟½80°C. Avoid Repeated Freeze Thaw Cycles. |
| Endotoxin | ≤ 1.0 EU/mg as determined by the LAL method |
| Purity | >95% by SDS-PAGE and HPLC |
| Formulation | Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free. |
| Purification Method | This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
| Specificity | Detects human RANK Ligand. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Denosumab. |
| Species Reactivity | Human |
| Target | RANKL |
| Shipping Conditions | Blue ice |
| background | Denosumab biosimilar is a human IgG2 monoclonal antibody that binds to human RANKL. Denosumab has an approximate molecular weight of 147 kDa and is produced in genetically engineered mammalian (Chinese hamster ovary) cells. |
| Other names | Tumor necrosis factor ligand superfamily member 11, Tnfsf11, Osteoclast differentiation factor, ODF, Osteoprotegerin ligand, OPGL, Receptor activator of nuclear factor kappa-B ligand, TNF-related activation-induced cytokine, TRANCE, CD254, Rank Ligang |
| UniProt | O14788 |
| Buffer | ICH3001-100ml ICH3002-100ml ICH3003-100ml |
| Sequence | https://www.imgt.org/mAb-DB/ |
Product Benefits:
ichorbio's Denosumab Biosimilar - Research Grade is manufactured in a cGMP compliant facility.
Size:
ichorbio's research grade denosumab biosimilar is available in the following sizes: 5mg, 10mg, 20mg, 50mg, 100mg ichorbio regularly manufactures bulk multi-gram amounts of our denosumab biosimilar - please contact us for pricing.
Isotype Control:
Write Your Own Review
Who Viewed This Also Viewed
