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Girentuximab Biosimilar - Research Grade
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Girentuximab Biosimilar - Research Grade
| Concentration | 5mg/ml |
|---|---|
| Isotype | Human IgG1 |
| Host | CHO cells |
| Use | Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
| Application Notes | This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients. |
| Applications | Functional Assays |
| Storage | This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C. |
| Endotoxin | ≤ 1.0 EU/mg as determined by the LAL method |
| Purity | >95% by SDS-PAGE |
| Formulation | Sterile, preservative-free, solution in PBS. BSA and Azide free. |
| Purification Method | This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
| Specificity | Detects human Carbonic Anhydrase IX. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Girentuximabï؟½Biosimilar - Research Grade. |
| Species Reactivity | Human |
| Target | Carbonic Anhydrase IX |
| Shipping Conditions | Blue ice |
| background | RUO girentuximab binds to the extracellular proteoglycan (PG)-like domain, which is unique to CA IX compared to other isoforms and lies adjacent to the catalytic domain. In addition to therapy, girentuximab has also been utilized as an imaging agent. |
| Other names | CAIX, CA-IX |
| UniProt | Q16790 |
| Buffer | ICH3002 |
| Sequence | https://www.imgt.org/mAb-DB/ |
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