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Monalizumab Biosimilar - Research Grade
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Monalizumab Biosimilar - Research Grade
| Concentration | 5mg/ml |
|---|---|
| Isotype | Human IgG4 |
| Host | CHO cells |
| Use | Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
| Application Notes | This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients. |
| Applications | Functional Assays |
| Storage | This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C. |
| Endotoxin | ≤ 1.0 EU/mg as determined by the LAL method |
| Purity | >95% by SDS-PAGE |
| Formulation | Sterile, preservative-free, solution in PBS. BSA and Azide free. |
| Purification Method | This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
| Specificity | Detects human CD159a. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Monalizumab. |
| Species Reactivity | Human |
| Target | NKG2A |
| Shipping Conditions | Blue ice |
| background | RUO monalizumab is a blocking antibody that prevents the inhibition of CD8+ T cells and NK cell by tumor cells expressing HLA-E. By acting simultaneously on innate and adaptive immunity, monalizumab may re-establish a broad anti-tumor response. |
| Other names | KLRC1,NKG2A,CD159a,CD94 |
| UniProt | P26715 |
| Buffer | ICH3002 |
| Sequence | https://www.imgt.org/mAb-DB/ |
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