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Anti-Mouse ICAM-1 (BE29G1) In Vivo Antibody - Low Endotoxin
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Anti-Mouse ICAM-1 (BE29G1) In Vivo Antibody - Low Endotoxin
| Concentration | 0.5 mg/ml |
|---|---|
| Isotype | Rat IgG2a |
| Host | Rat |
| Use | Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
| Application Notes | Blocking: This antibody blocks the binding LFA-1 (CD11a/CD18) to ICAM-1. The antibody is suitable for studies of inflammation, lymphocyte differentiation, and lymphocyte activation. Each investigator should determine their own optimal working dilution fo |
| Applications | Immunoprecipitation, Western Blot, Blocking |
| Storage | anti-ICAM-1 In Vivo Antibody - Low Endotoxin (BE29G1) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at ï؟½80°C. Avoid Repeated Freeze Thaw Cycles. |
| Endotoxin | ≤ 1.0 EU/mg as determined by the LAL method |
| Purity | >95% by SDS-PAGE and HPLC |
| Formulation | 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. |
| Purification Method | This monoclonal antibody was purified using Protein G |
| Specificity | Anti-ICAM-1 In Vivo Antibody - Low Endotoxin (BE29G1) recognizes the (Mr 95 kD) cell surface glycoprotein known as intracellular adhesion molecule ICAM-1. ICAM-1 is the receptor for LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). |
| Species Reactivity | Mouse |
| Target | ICAM-1 |
| Shipping Conditions | Blue ice |
| background | Intercellular adhesion molecule-1 (ICAM-1) is one of an important cell adhesion molecules (CAMs) family transmembrane glycoprotein and is critical for the firm arrest and transmigration of leukocytes out of blood vessels and into tissues. ICAM-1 is consti |
| Other names | Intercellular adhesion molecule 1, Icam1, MALA-2, MyD10, CD54 |
| clone | BE29G1 |
| UniProt | P13597 |
| Buffer | ICH3001-100ml ICH3002-100ml ICH3003-100ml |
| Antigen Distribution | The CD54 antigen is present on endothelial cells, lymphocytes, epithelial cells, dendritic cells and keratinocytes. It has been demonstrated that ICAM-1 enhances T-cell activation. |
| Immunogen | Purified Recombinant Mouse ICAM-1 (>98%) |
| Aggregation | Aggregation level ≤ 5% |
| Antibodies against the same target | Anti-ICAM-1 In Vivo Antibody - Low Endotoxin [15.2] (ICH1027) |
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