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Urabrelimab Biosimilar - Research Grade
$710.00 - $6,900.00
Urabrelimab Biosimilar - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
CD47ï؟½
Concentration
5mg/ml
Isotype
IgG4 - kappa
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
Q08722;Q08722;Q61735;P97829;Q08722;Q61735;P97829;;Q61735
Shipping Conditions
Blue ice
Background
CD47 is a broadly expressed 'don't eat me' signal that engages SIRPalpha to limit macrophage phagocytosis, making it a flagship target in cancer immunotherapy research. This IgG4 recombinant human antibody is an unconjugated, non-therapeutic analog of urabrelimab directed against CD47 and is intended for research use only (RUO). The low-endotoxin formulation is suitable for in vivo studies and is manufactured in scalable milligram to gram quantities for high-throughput and heavy-usage laboratories. It works well as a phagocytosis-checkpoint control and functional reagent across in vitro engulfment assays, ADCC studies, and preclinical tumor models.
Other Names
CD47, IAP, MER6, OA3, CD47 molecule, integrin associated protein
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Delivery Time
3-4 weeks
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