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Theralizumab Biosimilar - Research Grade
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heralizumab Biosimilar - Research Grade
| Product Specific Citations | |
|---|---|
| Concentration | 5mg/ml |
| Isotype | Human IgG4 |
| Host | CHO cells |
| Use | Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
| Application Notes | This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients. |
| Applications | Functional Assays |
| Storage | This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C. |
| Endotoxin | ≤ 1.0 EU/mg as determined by the LAL method |
| Purity | >95% by SDS-PAGE |
| Formulation | Sterile, preservative-free, solution in PBS. BSA and Azide free. |
| Purification Method | This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
| Specificity | Detects human CD28. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Theralizumab. |
| Species Reactivity | Human |
| Target | CD28 |
| Shipping Conditions | Blue ice |
| background | Theralizumab GN1412 is a humanised monoclonal antibody that not only binds to, but is a strong agonist for, the CD28 receptor of the immune systemï؟½s T cells. CD28 is the co-receptor for the T cell receptor; It binds to receptors on the interacting partn |
| Other names | TGN1412, CD28-SuperMAB, TAB08 |
| UniProt | P10747 |
| Buffer | ICH3002 |
| Sequence | https://www.imgt.org/mAb-DB/ |
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