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Tuvonralimab Biosimilar - Research Grade
$710.00 - $6,900.00
Tuvonralimab Biosimilar - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
CTLA4ï؟½
Concentration
5mg/ml
Isotype
IgG1 - kappa
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
P09793;P16410
Shipping Conditions
Blue ice
Background
As a co-inhibitory receptor that dampens T-cell priming, CTLA-4 ranks among the most studied immune checkpoints in oncology research. This recombinant human IgG1 antibody is an unconjugated, non-therapeutic analog of tuvonralimab targeting CTLA-4, supplied for research use only (RUO). It is formulated to a low-endotoxin standard suited to in vivo applications and produced in scalable milligram to gram quantities so that bulk and high-throughput laboratories never run short. Investigators commonly deploy it as a checkpoint-blockade control and functional reagent across in vitro T-cell activation assays, ADCC studies, and preclinical tumor immunotherapy models.
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Delivery Time
3-4 weeks
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