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Anti-Human TIM-3 (IB19) Antibody
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Species Reactivity
Human
Target
Tim-3
Concentration
5mg/ml
Isotype
Human IgG4 S228P Kappa
Size
0.1mg
Uniprot
Q8TDQ0
Shipping Conditions
Blue ice
Background
Tim-3 (HAVCR2) is an inhibitory checkpoint receptor implicated in T-cell exhaustion and the regulation of innate and adaptive immunity, drawing strong interest across immuno-oncology. Clone IB19 is a human IgG4 (S228P) monoclonal antibody recognising human Tim-3 and is well suited to functional assays examining checkpoint signalling and immune-cell behaviour. Anti-Tim-3 clone IB19 is prepared in a low-endotoxin format compatible with in vivo use and is manufactured in scalable milligram (mg) to gram (g) quantities for bulk and high-throughput laboratories. Offered for research use only as a non-therapeutic reagent, IB19 provides consistent performance and lot-to-lot reproducibility for human immunology research.
Specificity
Detects human Tim-3.
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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