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Tocilizumab Biosimilar - Research Grade
$315.00 - $19,890.00
Tocilizumab Biosimilar - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE and HPLC
Species Reactivity
Human
Target
IL-6 receptor
Concentration
1.0 - 5.0 mg/ml
Isotype
Human IgG1 Kappa
Host
Humanized
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Storage
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation
Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity
Detects human IL-6 receptor. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Tocilizumab.
Shipping Conditions
Blue ice
Background
The interleukin-6 receptor (IL-6R) mediates the activity of the pleiotropic cytokine IL-6 and is a key target in inflammation and autoimmunity research. This research-grade anti-human IL-6R recombinant monoclonal antibody is an unconjugated, non-therapeutic analog of tocilizumab, built around the IL-6 receptor for research use only. Manufactured to in vivo standards as an ultra-pure, low-endotoxin human IgG1-kappa, it is supplied in scalable milligram to gram quantities for high-throughput and bulk laboratories. It serves as a dependable control and active reagent across preclinical applications, including receptor-blocking assays, in vitro screening of IL-6 signalling, and in vivo inflammatory disease models.
Other Names
IL6R
Uniprot
P08887
Buffer
ICH3001-100ml
ICH3002-100ml
ICH3003-100ml
Sequence
https://www.imgt.org/mAb-DB/
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