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Trastuzumab Biosimilar - Research Grade
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Bulk Trastuzumab Biosimilar - Research Grade
Product Specific Citations:
Pougoue Ketchemen et al. Effectiveness of [67Cu]Cu-trastuzumab as a theranostic against HER2-positive breast cancer. Eur J Nucl Med Mol Imaging (2024).
Product Benefits:
ichorbio's Trastuzumab Biosimilar - Research Grade is manufactured in a cGMP compliant facility. ichorbio: the best antibodies for in vivo research.
Size:
ichorbio's research grade trastuzumab biosimilar is available in the following sizes: 5mg, 10mg, 20mg, 50mg, 100mg ichorbio regularly manufactures bulk multi-gram amounts of our trastuzumab biosimilar - please contact us for pricing.
Target:
ErbB2
Clone:
n/a
Isotype:
IgG1 kappa
Other Names:
Receptor tyrosine-protein kinase erbB-2, MLN 19, HER2, HER2/neu
Host:
Humanized
Species Reactivity:
Human
Specificity:
Detects human ErbB2.
Purification Method:
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Background:
Trastuzumab is a humanized IgG1 kappa monoclonal antibody that selectively binds with high affinity to the extracellular domain of the human epidermal growth factor receptor 2 protein, HER2. Trastuzumab is produced by recombinant DNA technology in a mammalian cell (Chinese Hamster Ovary).
Concentration:
1.0 - 5.0 mg/ml
Formulation:
Sterile, clear and colorless liquid with a pH of about 6.0, containing trehalose dihydrate , histidine monohydrate hydrochloride, histidine, polysorbate 20, without preservatives. pH 6.0. BSA and Azide free.
Purity:
>95% by SDS-PAGE and HPLC
Endotoxin:
≤ 0.75 EU/mg as determined by the LAL method
Storage:
Trastuzumab Biosimilar - Research Grade is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Applications:
Functional Assays
Application Notes:
Each investigator should determine their own optimal working dilution for specific applications.
Use: ichorbio's trastuzumab biosimilar is for research use only (RUO). Isotype Control:
Bulk Trastuzumab Biosimilar - Research Grade
| Product Specific Citations | |
|---|---|
| Concentration | 7.9mg/ml |
| Isotype | IgG1 kappa |
| Host | Humanized |
| Use | Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
| Storage | Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at ï؟½80°C. Avoid Repeated Freeze Thaw Cycles. |
| Endotoxin | ≤ 1.0 EU/mg as determined by the LAL method |
| Purity | >95% by SDS-PAGE and HPLC |
| Formulation | Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free. |
| Purification Method | This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
| Specificity | Detects human ErbB2. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Trastuzumab. |
| Species Reactivity | Human |
| Target | HER2 |
| Shipping Conditions | Blue ice |
| background | Trastuzumab is a humanized IgG1 kappa monoclonal antibody that selectively binds with high affinity to the extracellular domain of the human epidermal growth factor receptor 2 protein, HER2. Trastuzumab is produced by recombinant DNA technology in a mamma |
| Other names | Receptor tyrosine-protein kinase erbB-2, MLN 19, HER2, HER2/neu |
| UniProt | P04626 |
| Buffer | ICH3001-100ml ICH3002-100ml ICH3003-100ml |
| Sequence | https://www.imgt.org/mAb-DB/ |
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