Trastuzumab Biosimilar - Research Grade

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SKU
ICH4013
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$315.00 - $19,890.00

Bulk Trastuzumab Biosimilar - Research Grade

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Product Specific Citations

Ketchemen JP et al. Effectiveness of [67Cu]Cu-trastuzumab as a theranostic against HER2-positive breast cancer. Eur J Nucl Med Mol Imaging (2024).

Ketchemen, JP et al. Preclinical characterization of 3p-C-DEPA-NCS and 3p-C-DEPA-TFP-PEG4 as potential Actinium-225 bifunctional chelators using DOTA-NCS and macropa-NCS as benchmarks., 17 June 2025, PREPRINT (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-6813431/v1]

Ketchemen, JP et al. Complete Remissions of HER2-Positive Trastuzumab-Resistant Xenografts Using a Potent [225Ac]Ac-Labeled Anti-HER2 Antibody–Drug Radioconjugate. Clin Cancer Res (2025) 31 (4): 685–696.

Species Reactivity Human
Target HER2
Concentration 1.0 - 5.0 mg/ml
Isotype Human IgG1 Kappa
Host Humanized
Use Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Storage Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at ï؟½80°C. Avoid Repeated Freeze Thaw Cycles.
Endotoxin ≤ 1.0 EU/mg as determined by the LAL method
Purity >95% by SDS-PAGE and HPLC
Formulation Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purification Method This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity Detects human ErbB2. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Trastuzumab.
Shipping Conditions Blue ice
background Trastuzumab is a humanized IgG1 kappa monoclonal antibody that selectively binds with high affinity to the extracellular domain of the human epidermal growth factor receptor 2 protein, HER2. Trastuzumab is produced by recombinant DNA technology in a mamma
Other names Receptor tyrosine-protein kinase erbB-2, MLN 19, HER2, HER2/neu
UniProt P04626
Buffer ICH3001-100ml ICH3002-100ml ICH3003-100ml
Sequence https://www.imgt.org/mAb-DB/
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