Tislelizumab Biosimilar - Research Grade

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SKU
ICH5004
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$315.00 - $19,890.00

Tislelizumab Biosimilar - Research Grade

Endotoxin
<1 EU/mg Determined by LAL gel clotting assay
Purity
>95% by SDS-PAGE and HPLC
Species Reactivity
Human
Target
PD-1
Concentration
1.0 - 5.0 mg/ml
Isotype
Human IgG4
Host
Humanized
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Applications
Functional Assays
Storage
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation
Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity
Detects human PD-1. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Tislelizumab.
Shipping Conditions
Blue ice
Background
Programmed death-1 (PD-1) signalling dampens effector T-cell function, making it a key handle for immuno-oncology studies. This antibody is an unconjugated, non-therapeutic analog of tislelizumab directed at human PD-1 and validated for functional assays. It is provided for research use only, formulated with low endotoxin for in vivo suitability, and produced in scalable milligram to gram quantities for bulk and high-throughput laboratories. Typical uses include receptor-blockade controls, T-cell activation assays, in vitro screening, in vivo tumour models, and reference applications during biologics development, with reliable lot-to-lot reproducibility across high-throughput experimental campaigns.
Other Names
Programmed cell death protein 1, Pdcd1, CD279
Uniprot
Q15116
Buffer
ICH3002
Sequence
https://www.imgt.org/mAb-DB/
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