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Nesvacumab Biosimilar - Research Grade
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Nesvacumab Biosimilar - Research Grade
| Concentration | 5mg/ml |
|---|---|
| Isotype | Human IgG1 |
| Host | CHO cells |
| Use | Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
| Application Notes | This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients. |
| Applications | Functional Assays |
| Storage | This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C. |
| Endotoxin | ≤ 1.0 EU/mg as determined by the LAL method |
| Purity | >95% by SDS-PAGE |
| Formulation | Sterile, preservative-free, solution in PBS. BSA and Azide free. |
| Purification Method | This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype. |
| Specificity | Detects human Ang-2. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Nesvacumab. |
| Species Reactivity | Human |
| Target | Angiopoietin 2 |
| Shipping Conditions | Blue ice |
| background | RUO nesvacumab is an experimental monoclonal antibody originally designed for the treatment of cancer. It targets the protein angiopoietin 2. As of May 2017, it is in Phase II clinical trials for the treatment of diabetic macular edema. |
| Other names | ANGPT2, ANG2 |
| UniProt | O15123 |
| Buffer | ICH3002 |
| Sequence | https://www.imgt.org/mAb-DB/ |
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