Naptumomab Biosimilar - Research Grade

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SKU

ICH5007

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Naptumomab Biosimilar - Research Grade

Product Details:

ichorbio's naptumomab biosimilar is for Research Use Only (RUO)

Size:

ichorbio's RUO naptumomab biosimilar is available in the following sizes: 1mg, 5mg, 10mg, 20mg, 50mg, 100mg ichorbio regularly manufactures bulk multi-gram amounts of this biosimilar - please contact us for pricing.

Target:

5T4

Isotype:

IgG1 kappa

Other Names:

Naptumomab estafenatox, ABR-217620

Host:

CHO cells

Species Reactivity:

Human

Specificity:

Detects human 5T4.

Purification Method:

This recombinant protein was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Concentration:

1.0 - 5.0 mg/ml

Formulation:

Sterile, preservative-free, solution in PBS. BSA and Azide free.

Purity:

>95% by SDS-PAGE and HPLC

Endotoxin:

≤ 1.0 EU/mg as determined by the LAL method

Storage:

Naptumomab Biosimilar - Research Grade is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Applications:

Functional Assays

Application Notes:

Each investigator should determine their own optimal working dilution for specific applications.

Use: ichorbio's naptumomab biosimilar is for research use only (RUO). Isotype Control:

Bulk Human IgG1 Isotype Control (IB1) [ICH2254]

More Information
Concentration	7.7mg/ml
Isotype	IgG1 kappa
Host	CHO cells
Use	Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Application Notes	This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Applications	Functional Assays
Storage	This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Endotoxin	≤ 1.0 EU/mg as determined by the LAL method
Purity	>95% by SDS-PAGE
Formulation	Sterile, preservative-free, solution in PBS. BSA and Azide free.
Purification Method	This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity	Detects human 5T4. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Naptumomab.
Species Reactivity	Human
Target	5T4
Shipping Conditions	Blue ice
background	Naptumomab is a fusion protein consisting of the antigen-binding fragment (Fab) of a monoclonal antibody with the superantigen staphylococcal enterotoxin A (SEA/E-120, "estafenatox"). The Fab binds to 5T4, an antigen expressed by various tumor cells, and
Other names	Naptumomab estafenatox, ABR-217620
UniProt	Q13641
Buffer	ICH3002
Sequence	https://www.imgt.org/mAb-DB/