Secukinumab Biosimilar – Research Grade [ICH4033]

ichorbio’s Secukinumab Biosimilar – Research Grade is manufactured in a cGMP compliant facility.

ichorbio’s research grade secukinumab biosimilar is available in the following sizes:
5mg, 10mg, 20mg, 50mg,100mg
ichorbio regularly manufactures bulk multi-gram amounts of our secukinumab biosimilar – please contact us for pricing.

IL-17A

n/a

IgG1 kappa

Interleukin-17A, IL17A, CTLA-8, CTLA8

Humanized

Human

Detects human IL17A. This non-therapeutic antibody uses the same variable region sequence as the therapeutic antibody Secukinumab. ichorbio’s Secukinumab biosimilar is for research use only (RUO).

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Secukinumab is a recombinant human monoclonal IgG1/κ antibody that binds specifically to IL-17A. It is expressed in a recombinant Chinese Hamster Ovary (CHO) cell line. Secukinumab has a molecular mass of approximately 151 kDa; both heavy chains of secukinumab contain oligosaccharide chains.

1.0 – 5.0 mg/ml

Sterile, preservative-free, clear to milky white, colorless to slightly yellow solution, with a pH of 5.8, containing L-histidine/histidine monohydrate hydrochloride, polysorbate 80, and sucrose. BSA and Azide free.

>95% by SDS-PAGE and HPLC

≤ 0.75 EU/mg as determined by the LAL method

Secukinumab Biosimilar – Research Grade is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.

Functional Assays

Each investigator should determine their own optimal working dilution for specific applications.