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Secukinumab Biosimilar - Research Grade
$315.00 - $19,890.00
Secukinumab Biosimilar - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE and HPLC
Species Reactivity
Human
Target
IL17A
Concentration
1.0 - 5.0 mg/ml
Isotype
Human IgG1 Kappa
Host
Humanized
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Storage
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation
Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity
Detects human IL17A. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Secukinumab.
Shipping Conditions
Blue ice
Background
Interleukin-17A (IL-17A) is a pro-inflammatory cytokine central to Th17 responses and is heavily studied across psoriasis, arthritis, and other autoimmune settings. Presented as a research-grade reagent, this unconjugated, non-therapeutic analog of secukinumab targets human IL-17A for cytokine-neutralisation work. It is intended for research use only, purified to a low-endotoxin standard suitable for in vivo experiments, and produced in scalable milligram to gram quantities for laboratories with intensive throughput. Applications include IL-17A blockade assays, inflammatory signalling studies, in vitro screening, in vivo disease models, and use as a defined comparator in biologics development.
Other Names
Interleukin-17A, IL17A, CTLA-8, CTLA8
Uniprot
Q16552
Buffer
ICH3001-100ml
ICH3002-100ml
ICH3003-100ml
Sequence
https://www.imgt.org/mAb-DB/
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