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Anti-Human CD22 (IB14) Antibody
Endotoxin
<1EU/mg Determined by LAL gel clotting assay
Purity
≥95% monomer by analytical SEC, >95% by SDS Page
Species Reactivity
Human
Target
CD22
Concentration
1.0 - 5.0 mg/ml
Isotype
Human IgG1 (E356D/M358L)-kappa
Size
0.1mg
Uniprot
P20273
Shipping Conditions
Blue ice
Background
CD22 (Siglec-2) is an inhibitory co-receptor on B cells that fine-tunes B-cell receptor signalling and is a frequently studied marker in B-cell biology and lymphoma research. Clone IB14 is a human IgG1 monoclonal antibody recognising human CD22 and is suitable for functional assays exploring B-cell signalling and antigen engagement. Anti-CD22 clone IB14 is prepared in a low-endotoxin format compatible with in vivo use and is manufactured in scalable milligram (mg) to gram (g) quantities for bulk and high-throughput laboratories. Supplied for research use only as a non-therapeutic reagent, IB14 offers consistent, reproducible performance for human B-cell immunology studies.
Other Names
Sialic acid binding Ig-like lectin 2, SIGLEC2, SIGLEC-2, B-lymphocyte cell adhesion molecule, BL-CAM, Leu-14
Clone
IB14
Specificity
Detects human CD22
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C or –80°C. Avoid Repeated Freeze Thaw Cycles.
Application Notes
This antibody is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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