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Pertuzumab Biosimilar - Research Grade
$315.00 - $19,890.00
Pertuzumab Biosimilar - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE and HPLC
Species Reactivity
Human
Target
HER2
Concentration
1.0 - 5.0 mg/ml
Isotype
Human IgG1 Kappa
Host
Humanized
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Storage
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Formulation
Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity
Detects human HER2. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Pertuzumab.
Shipping Conditions
Blue ice
Background
HER2 (ERBB2) is a receptor tyrosine kinase that drives proliferative signalling and is amplified in a meaningful fraction of breast and gastric cancers, making it a benchmark oncology target. This research-grade anti-HER2 recombinant monoclonal antibody is an unconjugated, non-therapeutic analog of pertuzumab built to recognise the dimerisation domain of human HER2. Intended strictly for research use only, it is purified to a low-endotoxin standard suitable for in vivo work and produced in scalable milligram to gram quantities for heavy-usage, high-throughput laboratories. Typical applications span receptor-blockade controls, in vitro screening, ADCC studies, in vivo tumour models, and biologics characterisation.
Other Names
Receptor tyrosine-protein kinase erbB-2, MLN 19, HER2, HER2/neu
Uniprot
P04626
Buffer
ICH3001-100ml
ICH3002-100ml
ICH3003-100ml
Sequence
https://www.imgt.org/mAb-DB/
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