Otelixizumab Biosimilar - Research Grade

Human

CD3E

5mg/ml

Human IgG1 (N297A/E356D/M358L)-Lambda2(K83R)

CHO Cells

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.

Functional Assays

This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.

Sterile, preservative-free, solution in PBS. BSA and Azide free.

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Detects human CD3E

Blue ice

CD3 epsilon (CD3E) is an invariant component of the T-cell receptor complex and a central trigger for T-cell activation in immunology research. This recombinant anti-human CD3E antibody is an unconjugated, non-therapeutic analog of otelixizumab, intended for research use only (RUO). Carrying an Fc-silenced design, it is manufactured to in vivo standards with low endotoxin and supplied in scalable milligram (mg) to gram (g) quantities for bulk and high-throughput laboratories. It is well suited to functional assays, T-cell stimulation and tolerance-induction studies, defined controls, and in vivo models of T-cell biology, with the reproducibility expected for heavy-usage settings.

CD3E, IMD18, T3E, TCRE, CD3e molecule, CD3epsilon, CD3 epsilon subunit of T-cell receptor complex

P07766

ICH3002

https://www.imgt.org/mAb-DB/