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Anti-Mouse MAdCAM-1 (MECA-367) In Vivo Antibody - Low Endotoxin

Name: Anti-Mouse MAdCAM-1 (MECA-367) In Vivo Antibody - Low Endotoxin
SKU: ICH1215
Price: 400 USD
Availability: InStock

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ICH1215

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$400.00 - $2,945.00

Anti-Mouse MAdCAM-1 (MECA-367) In Vivo Antibody - Low Endotoxin

Endotoxin

≤ 1.0 EU/mg as determined by the LAL method

Purity

>95% by SDS-PAGE and HPLC

Species Reactivity

Mouse

Target

MAdCAM-1

Concentration

1.0 - 5.0 mg/ml

Isotype

Rat IgG2a kappa

Host

Rat

Aggregation

Aggregation level ≤ 5%

Immunogen

MAdCAM-1

Buffer

ICH3001-100ml ICH3002-100ml ICH3003-100ml

Uniprot

Q61826

Shipping Conditions

Blue ice

Background

Lymphocyte recruitment to gut mucosa depends on MAdCAM-1, an addressin expressed on mucosal endothelium that binds integrin alpha4beta7 to direct immune-cell homing. The rat IgG2a kappa monoclonal clone MECA-367 targets mouse MAdCAM-1 and is validated for in vivo work. This MECA-367 antibody is offered low in endotoxin for in vivo use and produced in scalable milligram to gram quantities to support high-throughput and heavy-usage laboratories. Designated for research use only and non-therapeutic, it provides reliable batch-to-batch consistency for studies of mucosal immunity, lymphocyte trafficking, and gut inflammation in mouse models.

Other Names

Mucosal addressin cell adhesion molecule-1

Clone

MECA-367

Purification Method

This monoclonal antibody was purified using Protein G

Formulation

This antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.

Storage

This low endotoxin antibody is stable when stored at 2-8°C for at least four (4) weeks. For long-term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.

Applications

In vivo

Application Notes

This isotype control antibody should be used at the same concentration as the primary antibody.

Use

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

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