Pig CD16a Protein (In Vivo Grade, Ultra-Low Endotoxin)

Pig (sus scrofa domesticus)

Pig CD16a Protein

Human embryonic kidney (HEK) 293 cells

Q28942

Ambient

CD16a (FcγRIIIa) is the activating Fc receptor that underpins NK-cell and macrophage antibody-dependent cytotoxicity, and its porcine equivalent is valuable for swine-based translational and xenotransplantation research. This recombinant pig CD16a ectodomain is expressed in HEK 293 cells and validated for SPR, BLI and ELISA, providing a defined reagent for cross-species Fc binding kinetics and ADCC-related characterization. Supplied for research use only in an in vivo grade, ultra-low-endotoxin format, it is produced at scalable milligram (mg) to gram (g) scale, giving bulk and high-throughput laboratories the quantities needed for systematic porcine Fc receptor studies.

CD16, CD16A, FCGR3, FCGR3A, FCGRIII, FCGRIIIA, FCR3, FCR3A, FCRIII, FCRIIIA, IGFR3, IGFR3A, IGFRIII, IGFRIIIA, Fc gamma R3, Fc gamma R3a, Fc gamma RIII, Fc gamma RIIIa, Fcg R3, Fcg R3a, Fcg RIII, Fcg RIIIa

The sequence of the extracellular domain of porcine CD16a (Ala 20-Gln 209) was fused with a C-terminal tag consisting of the AVI tag, TEV protease recognition sequence and a 10-His tag.

Lyophilized from sterile PBS, pH 7.4. No preservatives or cryoprotectants have been added. To obtain a final concentration of 1 mg/ml reconstitute 0.25 mg vials with 0.25 ml water and 1.0 mg vials with 1.0 ml water.

Lyophilized proteins are stable at ambient temperature for at least 2 weeks. If the protein is not to be used immediately then the protein should be stored in lyophilized form at -20 °C for up 12 months. Once the protein has been reconstituted we recommen

SPR, BLI, ELISA

Products are for research use only. Not for use in diagnostic or therapeutic procedures.