Gantenerumab Biosimilar - Research Grade

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SKU
ICH5009
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$315.00 - $19,890.00

Gantenerumab Biosimilar - Research Grade

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Species Reactivity
Human
Target
Beta Amyloid
Concentration
5mg/ml
Isotype
Human IgG1
Host
CHO cells
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Applications
Functional Assays
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity
Detects human Beta Amyloid. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Gantenerumab.
Shipping Conditions
Blue ice
Background
Aggregated beta-amyloid plaques are a defining feature of Alzheimer's disease and remain a key research target. As an unconjugated, non-therapeutic analog of gantenerumab, this research-grade antibody binds human beta-amyloid and is suitable for functional assays. It is supplied for research use only in a low-endotoxin format appropriate for in vivo experiments and manufactured in scalable milligram to gram quantities for high-throughput laboratories. Investigators apply it to amyloid-recognition assays, plaque-binding studies, in vitro screening, and in vivo models of amyloid pathology, supported by consistent lot-to-lot quality.
Uniprot
P05067
Buffer
ICH3002
Sequence
https://www.imgt.org/mAb-DB/
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