Ifinatamab deruxtecan - Research Grade

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SKU
ICH5204D
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Ifinatamab deruxtecan - Research Grade

Endotoxin
<1EU/mg Determined by LAL gel clotting assay
Purity
>95% Determined by SDS-PAGE
Target
B7-H3
Concentration
>1mg/ml
Isotype
Human IgG1
Host
CHO
Buffer
ICH3002
Shipping Conditions
Blue ice
Background
B7-H3 (CD276) is an immune-regulatory protein broadly overexpressed across solid tumours while largely spared in normal tissue, positioning it as a compelling antibody-drug-conjugate target. This research-grade analog of ifinatamab deruxtecan is a human IgG1 antibody-drug conjugate directed at B7-H3 and produced in CHO cells for preclinical investigation of targeted cytotoxic payload delivery. It is supplied as a non-therapeutic reagent for research use only (RUO). Prepared to in vivo grade standards as a low-endotoxin formulation and available in scalable milligram (mg) to gram (g) quantities, it enables cytotoxicity assays, internalization studies and in vivo tumour-model work in bulk and high-throughput laboratories.
Formulation
PBS, pH 7.4,Contains no stabilizers or preservatives. 0.2 μM filtered
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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