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Human IgG1 Isotype Control P331S/E430G
$315.00 - $5,200.00
Human IgG1 Isotype Control P331S/E430G
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Target
Hen Egg Lysozyme
Concentration
5mg/ml
Isotype
Human IgG1 (P331S/E430G)-kappa
Host
CHO Cells
Buffer
ICH3002
Shipping Conditions
Blue ice
Background
This human IgG1 isotype control carries the P331S substitution alongside the E430G mutation associated with enhanced Fc oligomerisation, and it recognises hen egg lysozyme rather than any mammalian antigen. As a negative control it provides the background and gating reference required to interpret specific antibody activity in flow cytometry, functional assays, and in vivo models. Matching the framework of engineered test antibodies, it isolates scaffold and Fc effects from true target engagement. The reagent is low in endotoxin and suitable for in vivo use, and it is manufactured in scalable milligram to gram quantities for high-throughput and bulk laboratories. Research use only.
Specificity
Human IgG1 with a P331S/E430G mutation
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This antibody is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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