Anti-Mouse CD317 (927) In Vivo Antibody - Low Endotoxin

Mouse

CD317

≤ 2.0 mg/ml

Rat IgG2a kappa

Rat

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

Each investigator should determine their own optimal working dilution for specific applications.

Depletion, Functional Assays, Flow Cytometry, Immunocytochemistry, Immunofluorescence Microscopy

This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.

Sterile, preservative-free, solution in PBS. BSA and Azide free.

This monoclonal antibody was purified using Protein G

Clone 927 activity is directed against murine CD317 (BST2; PDCA-1).

Blue ice

CD317 (BST-2, tetherin) is an interferon-induced antiviral protein that restricts the release of enveloped viruses and also marks plasmacytoid dendritic cells. Clone 927.0 is a rat IgG2a kappa monoclonal antibody recognising mouse CD317, validated for depletion, functional assays, flow cytometry, immunocytochemistry, and immunofluorescence microscopy. Anti-CD317 927.0 is supplied in a low-endotoxin format suitable for in vivo use and produced in scalable milligram-to-gram quantities for bulk and high-throughput laboratories. With consistent performance, it supports antiviral immunity and dendritic cell research, and is intended strictly for research use only as a non-therapeutic reagent.

927

Q8R2Q8

ICH3001-100ml ICH3002-100ml ICH3003-100ml

Murine CD317 is expressed by IFN-producing cells in naï؟½ve mouse spleen and by a wide variety of cell lines including T cells, mast cells, B cells, fibroblast cells, and pluripotent embryonal carcinoma cells. Additionally, mice challenged by influenza or

Mouse plasmacytoid dendritic cells

Aggregation level ≤ 5%