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Anti-Human PD-L1 (IB6) Antibody
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE and HPLC
Species Reactivity
Human
Target
PD-L1
Concentration
1.0 - 5.0 mg/ml
Isotype
Human IgG1 Kappa
Host
Humanized
Size
0.1mg
Uniprot
Q9NZQ7
Shipping Conditions
Blue ice
Background
PD-L1 is an inhibitory immune checkpoint ligand that engages PD-1 to dampen T-cell activity and is a cornerstone target in cancer immunotherapy research. Clone IB6 is a human IgG1-kappa monoclonal antibody against human PD-L1, suited to checkpoint-blockade and immune-modulation studies. Anti-PD-L1 clone IB6 is supplied in a low-endotoxin format suitable for in vivo use and produced in scalable milligram to gram quantities for bulk and high-throughput laboratories. With consistent lot-to-lot performance, IB6 is a dependable reagent for tumour immunology, T-cell biology, and preclinical checkpoint research. It is a non-therapeutic product intended strictly for research use only.
Other Names
Programmed cell death 1 ligand 1, Cd274, PDCD1 ligand 1, Programmed death ligand 1, B7 homolog 1, B7-H1, B7h1, Pdcd1l1, Pdcd1lg1, Pdl1, PDL-1
Clone
IB6
Specificity
Detects human PDL-1.
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Formulation
Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
Storage
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C or –80°C. Avoid Repeated Freeze Thaw Cycles.
Application Notes
This antibody is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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