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Tamgiblimab Biosimilar - Research Grade
$710.00 - $19,500.00
Tamgiblimab Biosimilar - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Species Reactivity
Human
Target
TIGIT
Concentration
5mg/ml
Isotype
Human IgG4 - kappa
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH2983
Uniprot
Q495A1
Shipping Conditions
Blue ice
Background
TIGIT is an inhibitory checkpoint receptor on T and NK cells that competes with co-stimulatory pathways and is a prominent target in cancer immunology research. This anti-human TIGIT recombinant monoclonal antibody is an unconjugated, non-therapeutic analog of tamgiblimab, supplied strictly for research use only. Built to demanding in vivo standards and formulated with low endotoxin, it is manufactured in scalable milligram (mg) to gram (g) quantities for bulk and high-throughput laboratories. It serves dependably in checkpoint blockade studies, NK- and T-cell functional assays, in vitro screening, and in vivo immuno-oncology disease models.
Specificity
Detects human TIGIT
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Delivery Time
4 weeks
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