Anti-Mouse DR5 (MD5-1) In Vivo Antibody - Low Endotoxin

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SKU
ICH1236
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$400.00 - $2,945.00

Anti-Mouse DR5 (MD5-1) In Vivo Antibody - Low Endotoxin

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE and HPLC
Species Reactivity
Mouse
Target
DR5
Concentration
≤ 2.0 mg/ml
Isotype
Armenian Hamster IgG
Host
Armenian Hamster
Aggregation
Aggregation level ≤ 5%
Immunogen
Mouse DR5-Ig fusion protein
Buffer
ICH3002-100ml
Uniprot
Q9QZM4
Shipping Conditions
Blue ice
Background
DR5 (TRAIL-R2) is a death-domain receptor that triggers apoptosis upon ligation and is widely studied in cancer cell-death pathways. Clone MD5-1 is an Armenian hamster IgG monoclonal antibody against mouse DR5 that acts as an agonist, validated for functional assays, flow cytometry, immunoprecipitation, and Western blotting. Anti-DR5 MD5-1 is supplied in a low-endotoxin format suitable for in vivo use and produced in scalable milligram to gram quantities for bulk and high-throughput laboratories. This non-therapeutic reagent, for research use only, gives reproducible, lot-consistent performance for apoptosis, TRAIL-pathway, and tumour cell-death research in mice.
Clone
MD5-1
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
This antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Storage
This low endotoxin antibody is stable when stored at 2-8°C for at least four (4) weeks. For long-term storage aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Applications
Agonist, Functional Assays, Flow Cytometry, Immunoprecipitation, Western Blotting
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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