Efgartigimod Biosimilar - Research Grade

Human

FcRn

5mg/ml

Human IgG1 (M252Y/S254T/T256E/H433K/N434F) Fc Fragment

CHO Cells

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.

Functional Assays

This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.

Sterile, preservative-free, solution in PBS. BSA and Azide free.

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Detects FcRn

Blue ice

The neonatal Fc receptor (FcRn) recycles IgG and albumin to extend their half-life, and its modulation is central to autoimmune and antibody-engineering research. This engineered Fc-fragment reagent is an unconjugated, non-therapeutic analog of efgartigimod that targets FcRn, supplied for research use only (RUO). Manufactured to in vivo standards with low endotoxin, it is offered in scalable milligram (mg) to gram (g) quantities for bulk and high-throughput laboratories. Applications include functional assays, FcRn-blockade and IgG-recycling studies, reproducible controls, and in vivo models of autoantibody-mediated disease, providing the consistency required for heavy-usage research.

P55899

ICH3002

https://www.imgt.org/mAb-DB/