Bulk Human IgG1 Isotype Control (IB1) D265A/N297A
ichorbio’s bulk Human IgG1 Isotype Control (IB1) D265A/N297A is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. It is suitable for in vivo use.
n/a. We mutated the CDR regions of a human IgG1 antibody to abolish binding to human proteins
ichorbio’s Human IgG1 Isotype Control (IB1) D265A/N297A is available in the following bulk sizes: 5mg, 25mg, 50mg and 100mg. ichorbio regularly manufactures multi-gram amounts of our human IgG1 antibody with D265A/N297A mutation – please contact us for pricing.
Human IgG1 kappa
This Human IgG1 isotype control recombinant antibody has been tested against selected human cells and tissues to assure minimal cross reactivity.
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Recombinant IgG1 human antibody with a replacement of aspartic acid by alanine at position 265 (D265A) and replacement of asparagine by alanine at position 297 (N2979A).
This Human IgG1 Isotype Control (IB1) is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 – 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and azide free
>95% by SDS-PAGE and HPLC
>98% by SDS-PAGE and HPLC
≤ 1.0 EU/mg as determined by the LAL method
≤ 0.75 EU/mg as determined by the LAL method
Aggregation level ≤ 5%
Aggregation level ≤ 1%
This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Flow Cytometry, Functional Assays
Each investigator should determine their own optimal working dilution for specific applications.
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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