Amivantamab Biosimilar - Research Grade

Human

EGFR + MET

5mg/ml

Human IgG1 (K214R/F405L/K409R)-kappa

CHO Cells

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.

Functional Assays

This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.

Sterile, preservative-free, solution in PBS. BSA and Azide free.

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Detects EGFRxMET

Blue ice

EGFR and MET are co-drivers of proliferative signalling and acquired resistance in lung and other carcinomas, making their dual targeting a key oncology research theme. This bispecific reagent is an unconjugated, non-therapeutic analog of amivantamab engaging EGFR and MET, supplied for research use only (RUO). It is produced to in vivo standards with low endotoxin and available in scalable milligram (mg) to gram (g) quantities for high-throughput laboratories. Use it in functional assays, dual-receptor-blockade and downregulation studies, reproducible controls, and in vivo tumour models that depend on consistent, well-characterised bispecific reagents for large experimental campaigns.

P00533;P08581

ICH3002

https://www.imgt.org/mAb-DB/