Magrolimab Biosimilar - Research Grade

Human

CD47

5mg/ml

Human IgG4

Human IgG4

Products are for research use only. Not for use in diagnostic or therapeutic procedures.

This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.

Functional Assays

This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.

Sterile, preservative-free, solution in PBS. BSA and Azide free.

This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.

Detects human CD47. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Magrolimab.

Blue ice

By engaging SIRP-alpha, CD47 transmits an anti-phagocytic signal that tumours exploit to evade macrophages, making it a key target in innate immuno-oncology. This research-grade antibody is an unconjugated, non-therapeutic analog of magrolimab directed at human CD47 and validated for functional assays. It is supplied for research use only in a low-endotoxin format suitable for in vivo experiments and produced in scalable milligram to gram quantities for high-throughput use. Typical uses include phagocytosis assays, CD47-SIRPa blockade studies, in vitro screening, in vivo tumour models, and biologics characterisation.

CD47, IAP, MER6, OA3, CD47 molecule, integrin associated protein

Q08722

ICH3002

https://www.imgt.org/mAb-DB/