Pozelimab Biosimilar - Research Grade

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SKU
ICH5295
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$315.00 - $19,890.00

Pozelimab Biosimilar - Research Grade

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Species Reactivity
Human
Target
C5
Concentration
5mg/ml
Isotype
Human IgG4 (S228P)-kappa
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
P01031
Shipping Conditions
Blue ice
Background
Complement component C5 governs the terminal complement pathway, generating the potent anaphylatoxin C5a and the membrane attack complex. Offered as an unconjugated, non-therapeutic analog of pozelimab, this research-grade anti-human C5 recombinant monoclonal antibody is intended for research use only. It is manufactured to in vivo quality standards, formulated for low endotoxin, and supplied in scalable milligram (mg) to gram (g) quantities for bulk and high-throughput laboratories. Typical applications include complement inhibition assays, in vitro functional screening, and in vivo models of complement-mediated disease, where it provides a dependable, reproducible reagent.
Other Names
REGN3918,REGN-3918,complement 5, C5a anaphylatoxin
Specificity
Detects human C5
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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