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Anti-CD80 (16-10A1) In Vivo Antibody - Low Endotoxin
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Bulk anti-CD80 In Vivo Antibody - Low Endotoxin (16-10A1)
Bio X Cell:
ICH1037 is up to 37% cheaper for industry than the equivalent products BE0024 (low endotoxin) from Bio X Cell. Product Benefits:
ichorbio's anti-CD80 In Vivo Antibody - Low Endotoxin (16-10A1) is manufactured in a cGMP compliant facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from Bio X Cell at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin (<0.5EU/mg) at an even higher purity (98% versus 95%). ichorbio: the best antibodies for in vivo research.
Target:CD80
Clone:16-10A1
Size:ichorbio's 16-10A1 in vivo antibody is available in the following bulk sizes: 1mg, 5mg, 25mg, 50mg and 100mg ichorbio regularly manufactures multi-gram amounts of our anti-CD80 16-10A1 clone - please contact us for pricing.
Isotype:Armenian Hamster IgG
Other Names:Activation B7-1 antigen, B7
Uniprot: Host:Armenian Hamster
Species Reactivity:Mouse, Rat
Specificity:Anti-CD80 In Vivo Antibody - Low Endotoxin (16-10A1) recognizes an epitope on Mouse CD80
Purification Method:This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Antigen Distribution:Mouse CD80 is expressed on Activated B-Cells, Activated T-Cells, macrophages, and dendritic cells.
Background:CD80 (B7-1) is a type I integral membrane protein related very closely to CD86 (B7-2). A main function of CD80 is the costimulation of T-cells through ligation of CD28 and CD152 (CTLA-4). T-cells activate with binding of CD28 to CD80 and binding of CD80 to CTLA-4 results in inhibition of T-cells. The clone 16-10A1 has the ability to block the costimulatory activity of CD80 while exhibiting no effect on the activity of CD86.
Immunogen:Purified Recombinant Mouse CD80 (>98%)
Concentration:1.0 mg/ml
Formulation:0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and Azide free.
Purity:>95% by SDS-PAGE and HPLC
>98% by SDS-PAGE and HPLC
Endotoxin:≤ 1.0 EU/mg as determined by the LAL method
≤ 0.75 EU/mg as determined by the LAL method
Aggregation:Aggregation level ≤ 5%
Aggregation level ≤ 1%
IMPACT Pathogen Test:We use the IMPACT test generated by IDEXX Laboratories to guarantee our Ultra Low Endotoxin antibodies are pathogen free. Our hamster antibodies are tested for: Mycoplasma spp Mycoplasma pulmonis Pneumonia virus of mice Kilham's rat virus Toolan's H1 virus Hamster parvovirus Lymphocytic choriomeningitis Minute virus of mice Theiler's murine encephalomyelitis virus Sendai virus Reovirus 3 Hantaan virus
Storage:This antibody is stable for at least 4 weeks when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at – 20°C or -80°C. Avoid repeated freeze thaw cycles.
Applications:Immunoprecipitation, Western Blot, Blocking, Flow Cytometry, IHC (Frozen)
Application Notes:Each investigator should determine their own optimal working dilution for specific applications.
Use:Products are for research use only.
Isotype Control:Armenian Hamster IgG Isotype Control for In Vivo - Low Endotoxin [PIP] (ICH2251)
Alternative Names:- Activation B7-1 antigen antibody
- B lymphocyte activation antigen B7 antibody
- B7 antibody
- B7-1 antibody
- B7-1 antigen antibody
- B7.1 antibody
- BB1 antibody
- CD28 antigen ligand 1 antibody
- CD28LG antibody
- CD28LG1 antibody
- CD80 antibody
- CD80 antigen (CD28 antigen ligand 1, B7-1 antigen) antibody
- CD80 antigen antibody
- CD80 molecule antibody
- Costimulatory factor CD80 antibody
- Costimulatory molecule variant IgV-CD80 antibody
- CTLA-4 counter-receptor B7.1 antibody
- LAB7 antibody
- T-lymphocyte activation antigen CD80 antibody
| Concentration | 1.0 mg/ml |
|---|---|
| Isotype | Armenian Hamster IgG |
| Host | Armenian Hamster |
| Use | Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
| Application Notes | Each investigator should determine their own optimal working dilution for specific applications. |
| Applications | Immunoprecipitation, Western Blot, Blocking, Flow Cytometry, IHC (Frozen) |
| Storage | anti-CD80 In Vivo Antibody - Low Endotoxin (16-10A1) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at ï؟½80°C. Avoid Repeated Freeze Thaw Cycles. |
| Endotoxin | ≤ 1.0 EU/mg as determined by the LAL method |
| Purity | >95% by SDS-PAGE and HPLC |
| Formulation | 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added. |
| Purification Method | This monoclonal antibody was purified using Protein A |
| Specificity | Anti-CD80 In Vivo Antibody - Low Endotoxin (16-10A1) recognizes an epitope on Mouse CD80 |
| Species Reactivity | Mouse |
| Target | CD80 |
| Shipping Conditions | Blue ice |
| background | CD80 (B7-1) is a type I integral membrane protein related very closely to CD86 (B7-2). A main function of CD80 is the costimulation of T-cells through ligation of CD28 and CD152 (CTLA-4). T-cells activate with binding of CD28 to CD80 and binding of CD80 t |
| Other names | Activation B7-1 antigen, B7 |
| clone | 16-10A1 |
| UniProt | Q00609 |
| Buffer | ICH3001-100ml ICH3002-100ml ICH3003-100ml |
| Antigen Distribution | Mouse CD80 is expressed on Activated B-Cells, Activated T-Cells, macrophages, and dendritic cells. |
| Immunogen | Purified Recombinant Mouse CD80 (>98%) |
| Aggregation | Aggregation level ≤ 5% |
| Related Antibody | Anti-CD80 In Vivo Antibody - Ultra Low Endotoxin [16-10A1] (ICH1037UL) |
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