Anti-Human CTLA4 (IB8) Antibody

In stock
SKU
ICH4025A-0.1mg
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$102.00
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE and HPLC
Species Reactivity
Human
Target
CTLA-4
Concentration
1.0 - 5.0 mg/ml
Isotype
Human IgG1 Kappa
Host
Humanized
Size
0.1mg
Uniprot
P16410
Shipping Conditions
Blue ice
Background
CTLA-4 is an inhibitory checkpoint receptor that competes with CD28 to limit early T-cell activation and is a foundational target in cancer immunology research. Clone IB8 is a human IgG1-kappa monoclonal antibody directed against human CTLA-4, suited to checkpoint-blockade and T-cell activation studies. Anti-CTLA-4 clone IB8 is supplied in a low-endotoxin format suitable for in vivo use and produced in scalable milligram to gram quantities for bulk and high-throughput laboratories. With dependable lot-to-lot consistency, IB8 is a robust reagent for tumour immunology and preclinical checkpoint research. It is a non-therapeutic product intended strictly for research use only.
Other Names
Ctla4, Cytotoxic T-lymphocyte protein 4, CD152
Clone
IB8
Specificity
Detects human CTLA-4.
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Formulation
Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
Storage
Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C or –80°C. Avoid Repeated Freeze Thaw Cycles.
Application Notes
This antibody is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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