Anti-Mouse TNFR2 (TR75-54.7) In Vivo Antibody - Low Endotoxin
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Bulk anti-TNFR2 In Vivo Antibody - Low Endotoxin (TR75-54.7)
| Product Specific Citations |
Chuah et al. Uncoupling immune trajectories of response and adverse events from anti-PD-1 immunotherapy in hepatocellular carcinoma. Journal of Hepatology (2022).
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| Concentration | 1.0 mg/ml |
| Isotype | Armenian Hamster IgG |
| Host | Armenian Hamster |
| Use | Products are for research use only. Not for use in diagnostic or therapeutic procedures. |
| Application Notes | Blocking: Clone TR75-54.7 antibody has been reported to block ligand-induced receptor signaling. Each investigator should determine their own optimal working dilution for specific applications. |
| Applications | Immunoprecipitation, Western Blot, Blocking, Flow Cytometry, ELISA |
| Storage | anti-TNFR2 In Vivo Antibody - Low Endotoxin (TR75-54.7) is stable for at least four (4) weeks when stored sterile at 2-8°C. For long-term storage aseptically aliquot in working volumes without diluting and store at ï؟½20°C in a manual defrost freezer. |
| Endotoxin | ≤ 1.0 EU/mg as determined by the LAL method |
| Purity | >95% by SDS-PAGE and HPLC |
| Formulation | 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added. |
| Purification Method | This monoclonal antibody was purified using Protein A |
| Specificity | Anti-TNFR2 In Vivo Antibody - Low Endotoxin (TR75-54.7) recognizes Mouse CD120 |
| Species Reactivity | Mouse |
| Target | TNFR2 |
| Shipping Conditions | Blue ice |
| background | Tumor necrosis factor receptor II (TNF-RII) is present on most cell types and is considered to play a prominent role in stimulation by TNF-alpha. TNFRII proteins are expressed by hematopoietic cells including macrophages, neutrophils, lymphocytes, thymocy |
| Other names | Tnfrsf1b, Tumor necrosis factor receptor superfamily member 1B, Tumor necrosis factor receptor 2, TNF-R2, Tumor necrosis factor receptor type II, TNF-RII, TNFR-II, p75, p80 TNF-alpha receptor, CD120b, Tnfr-2 |
| clone | TR75-54.7 |
| UniProt | P25119 |
| Buffer | ICH3001-100ml ICH3002-100ml ICH3003-100ml |
| Immunogen | Purified Recombinant Mouse TNF R2 |
| Aggregation | Aggregation level ≤ 5% |
Bio X Cell:
ICH1137 is up to 37% cheaper for industry than the equivalent product BE0247 from Bio X Cell.
Product Benefits:ichorbio's anti-TNFR2 In Vivo Antibody - Low Endotoxin (TR75-54.7) is manufactured in a cGMP compliant, ISO Quality Standard 9001:2015 facility. ichorbio's low endotoxin antibodies have half the endotoxin of comparable antibodies from Bio X Cell at less than 1.0 EU/mg. If ichorbio's low endotoxin antibodies are not low enough we also offer ultra low endotoxin antibodies which have even less endotoxin (<0.5EU/mg) at an even higher purity (98% versus 95%). ichorbio: the best antibodies for in vivo research.
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