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Negalstobart Biosimilar - Research Grade
$710.00 - $6,900.00
Negalstobart Biosimilar - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
LAG3ï؟½
Concentration
5mg/ml
Isotype
IgG4 - kappa
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
P18627
Shipping Conditions
Blue ice
Background
Lymphocyte-activation gene 3 (LAG3) is an inhibitory checkpoint receptor that dampens T-cell responses and has become a leading target in combination immuno-oncology research. We provide an unconjugated, non-therapeutic analog of negalstobart as a recombinant human IgG4 kappa antibody against LAG3, strictly for research use only (RUO). Formulated to a low-endotoxin standard for in vivo compatibility, it is manufactured in scalable milligram-to-gram lots that satisfy bulk and high-throughput laboratory demands. The reagent acts as a checkpoint-blockade control and active tool across in vitro screening, T-cell functional assays, preclinical immuno-oncology models, and biologics characterization.
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Delivery Time
3-4 weeks
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