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Lexatumumab Biosimilar - Research Grade
$710.00 - $6,900.00
Lexatumumab Biosimilar - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
TNFRSF10Bï؟½
Concentration
5mg/ml
Isotype
IgG1 - lambda2
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
O14763
Shipping Conditions
Blue ice
Background
TNFRSF10B (death receptor 5, DR5) triggers apoptosis when engaged, which has made it a focus of cancer cell-death research. This human IgG1, lambda2 antibody is an unconjugated, non-therapeutic analog of lexatumumab that binds DR5 for functional studies. Manufactured to a low-endotoxin standard compatible with in vivo experiments, it is offered in scalable milligram-to-gram quantities tailored to bulk and high-throughput laboratories. For research use only (RUO), it can serve as an agonist-style probe and control in apoptosis-induction assays, receptor-clustering experiments, in vitro tumor cell screening, and preclinical oncology models exploring the extrinsic cell-death pathway.
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Delivery Time
3-4 weeks
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