Marmoset CD16a Protein (In Vivo Grade, Ultra-Low Endotoxin)

Marmoset (Callithrix jacchus)

Marmoset CD16a Protein

Human embryonic kidney (HEK) 293 cells

A0A8I3WA45

Ambient

CD16a (FcγRIIIa) is the activating receptor behind NK-cell and macrophage ADCC, and a marmoset version aids effector-function research in this important non-human-primate model. This recombinant marmoset CD16a ectodomain, expressed in HEK 293 cells, is validated for SPR, BLI and ELISA and is well suited to cross-species Fc binding kinetics and ADCC-related characterization. The protein is non-therapeutic and for research use only, manufactured to in vivo grade with ultra-low endotoxin. With scalable milligram (mg) to gram (g) production, it equips high-throughput and bulk laboratories to study primate activating Fc receptor engagement reproducibly.

CD16, CD16A, FCGR3, FCGR3A, FCGRIII, FCGRIIIA, FCR3, FCR3A, FCRIII, FCRIIIA, IGFR3, IGFR3A, IGFRIII, IGFRIIIA, Fc gamma R3, Fc gamma R3a, Fc gamma RIII, Fc gamma RIIIa, Fcg R3, Fcg R3a, Fcg RIII, Fcg RIIIa

The sequence of the extracellular domain of marmoset CD16a (Glu 21-Gln 207) was fused with a C-terminal tag consisting of the AVI tag, TEV protease recognition sequence and a 10-His tag.

Lyophilized from sterile PBS, pH 7.4. No preservatives or cryoprotectants have been added. To obtain a final concentration of 1 mg/ml reconstitute 0.25 mg vials with 0.25 ml water and 1.0 mg vials with 1.0 ml water.

Lyophilized proteins are stable at ambient temperature for at least 2 weeks. If the protein is not to be used immediately then the protein should be stored in lyophilized form at -20 °C for up 12 months. Once the protein has been reconstituted we recommen

SPR, BLI, ELISA

Products are for research use only. Not for use in diagnostic or therapeutic procedures.