Izalontamab Biosimilar - Research Grade

Human

EGFRxHer3

>1mg/ml

Human IgG1 -kappa-scFv (heavy - lambda)2

CHO Cells

https://www.imgt.org/mAb-DB/

ICH3002

Blue Ice

EGFR and HER3 are receptor tyrosine kinases whose co-signaling drives proliferation in numerous epithelial tumors, a leading focus of oncology research. This research-grade, non-therapeutic biosimilar analog of izalontamab is a bispecific recombinant human IgG1-based antibody designed to engage both EGFR and HER3, supplied for research use only (RUO). It is purified to a low-endotoxin standard suitable for in vivo studies and manufactured in scalable milligram to gram quantities for high-throughput and bulk laboratories. The reagent supports dual-receptor binding and blocking assays, in vitro tumor-cell screening, control applications, and preclinical models of EGFR/HER3 co-targeting.

SI-1X6.4,SI-B001,SI-1

Ion Exchange Chromatography

Sterile, preservative-free, solution in PBS. BSA and Azide free.

This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.

Functional Assays

This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.

Products are for research use only. Not for use in diagnostic or therapeutic procedures.