Human IgG1 Isotype Control LALA/G237A

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SKU
ICH2254LALAGA
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$315.00 - $5,200.00

Human IgG1 Isotype Control LALA/G237A

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Target
Hen Egg Lysozyme
Concentration
5mg/ml
Isotype
Human IgG1 (L234A/L235A/G237A)-kappa
Host
CHO Cells
Buffer
ICH3002
Shipping Conditions
Blue ice
Background
Carrying the LALA mutations together with G237A for further reduction of Fcγ receptor binding, this human IgG1 control recognises hen egg lysozyme and has no specific target in mammalian systems. It functions as a matched negative control that sets background levels and gating cut-offs, allowing researchers to attribute observed signals to genuine antigen binding rather than the IgG1 backbone or residual effector activity. The reagent suits flow cytometry, functional assays, and controlled in vivo experiments. Formulated with low endotoxin for in vivo use, it is produced in scalable milligram to gram quantities to support bulk and high-throughput research. It is a non-therapeutic, research-use-only product.
Specificity
Human IgG1 with a LALA/G237A mutation
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This antibody is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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