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Human IgG1 Isotype Control LALA/F405L
$315.00 - $5,200.00
Human IgG1 Isotype Control LALA/F405L
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Target
Hen Egg Lysozyme
Concentration
5mg/ml
Isotype
Human IgG1 (L234A/L235A/F405L)-kappa
Host
CHO Cells
Buffer
ICH3002
Shipping Conditions
Blue ice
Background
This human IgG1 isotype control pairs the LALA effector-null mutations with the F405L substitution used in controlled Fab-arm exchange, and it is raised against hen egg lysozyme so it lacks any mammalian target. As a negative control it establishes the background and gating reference needed to interpret specific antibody activity in flow cytometry and functional readouts. Matching the IgG1 framework of test reagents, it cleanly separates scaffold-driven effects from true antigen engagement. It comes in a low-endotoxin, in-vivo-suitable format and is manufactured at scalable milligram to gram quantities for high-throughput and bulk applications. Provided for research use only.
Specificity
Human IgG1 with a LALA/F405L mutation
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This antibody is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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