Human IgG1 Fc plus hinge region

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SKU
ICH2267
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$315.00 - $5,200.00

Human IgG1 Fc plus hinge region

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>95% by SDS-PAGE
Target
Hen Egg Lysozyme
Concentration
5mg/ml
Isotype
Human IgG1
Host
CHO Cells
Buffer
ICH3002
Shipping Conditions
Blue ice
Background
This human IgG1 Fc-plus-hinge fragment provides the constant region and hinge of human IgG1 without an antigen-binding domain, serving as a format-matched control reagent for studies of Fc biology, FcγR and FcRn interactions, and Fc-fusion experiments. Because it lacks a variable region, it acts as a negative reference that isolates Fc-mediated effects from specific antigen engagement in functional and binding assays. The fragment is supplied low in endotoxin and suitable for in vivo use, and produced in scalable milligram to gram quantities to support bulk and high-throughput laboratories. It is a non-therapeutic reagent intended for research use only.
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This antibody is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
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