Emicizumab Biosimilar - Research Grade

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SKU
ICH5178
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$365.00 - $9,364.00

Emicizumab Biosimilar - Research Grade

Endotoxin
<1EU/mg Determined by LAL gel clotting assay
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
Factor IX + Factor X
Concentration
5mg/ml
Isotype
Human IgG4-kappa
Host
CHO Cells
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Applications
Functional Assays
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Purification Method
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Specificity
Detects human Factor IX and Factor X
Shipping Conditions
Blue ice
Background
Coagulation factors IX and X are central proteases of the intrinsic clotting cascade, of enduring interest in haemostasis and haemophilia research. Built as an unconjugated, non-therapeutic analog of emicizumab, this bispecific recombinant antibody bridges factor IX and factor X and is supplied strictly for research use only (RUO). It is manufactured to in vivo standards, carries low endotoxin, and is offered in scalable milligram (mg) to gram (g) batches for heavy-usage and high-throughput facilities. Applications include functional assays, factor-bridging and clotting studies, reproducible controls, and in vivo coagulation models requiring well-defined, dependable bispecific reagents.
Uniprot
P00740;P00742
Buffer
ICH3002
Sequence
https://www.imgt.org/mAb-DB/
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