Demcizumab Biosimilar - Research Grade

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SKU
ICH5472
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$710.00 - $6,900.00
Delivery Time : 4 weeks

Demcizumab Biosimilar - Research Grade

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
DLL4ï؟½
Concentration
5mg/ml
Isotype
IgG2 - kappa
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
Q9NR61
Shipping Conditions
Blue ice
Background
Delta-like ligand 4 (DLL4) is a Notch-pathway ligand that regulates angiogenesis and vascular sprouting, a focus of developmental and tumor-vasculature research. Offered as an unconjugated, non-therapeutic analog of demcizumab, this human IgG2-kappa recombinant antibody is intended for research use only (RUO). It is provided in a low-endotoxin, in vivo-suitable format and manufactured in scalable milligram-to-gram quantities for high-throughput laboratories. The antibody supports functional and ligand-blockade assays, Notch-signaling and angiogenesis studies, in vitro screening and preclinical tumor models examining DLL4 activity. Its low-endotoxin, in vivo-grade formulation and scalable milligram-to-gram supply make it dependable for repeat, high-volume experimentation.
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Delivery Time
3-4 weeks
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