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Azirkitug Biosimilar - Research Grade
Azirkitug Biosimilar - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
CCR8ï؟½
Concentration
5mg/ml
Isotype
IgG1 - kappa
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
P51685
Shipping Conditions
Blue ice
Background
The chemokine receptor CCR8 marks tumor-infiltrating regulatory T cells and has become a prominent target for selective Treg depletion strategies in cancer research. This product is an unconjugated, non-therapeutic analog of azirkitug, a human IgG1-kappa recombinant antibody intended strictly for research use only. Manufactured to in vivo-grade specifications with low endotoxin, it is provided in scalable milligram-to-gram quantities so that bulk and high-throughput laboratories can run extended studies without lot variability. It is well suited to functional assays, ADCC evaluation, immune-cell phenotyping and preclinical tumor immunology models exploring CCR8 biology.
Other Names
CC-CKR-8, CCR-8, CDw198, CKRL1, CMKBR8, CMKBRL2, CY6, GPRCY6, TER1, C-C motif chemokine receptor 8
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Delivery Time
3-4 weeks
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