Axatilimab Biosimilar - Research Grade

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SKU
ICH5366
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$710.00 - $6,900.00
Delivery Time : 4 weeks

Axatilimab Biosimilar - Research Grade

Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
CSF1Rï؟½
Concentration
5mg/ml
Isotype
IgG4 - kappa
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
P07333
Shipping Conditions
Blue ice
Background
Colony-stimulating factor 1 receptor (CSF1R) governs the differentiation, survival and recruitment of macrophages and microglia, making it a focal point in tumor-microenvironment and fibrosis research. This research-grade anti-CSF1R recombinant monoclonal is an unconjugated, non-therapeutic analog of axatilimab, expressed in CHO cells as a human IgG4-kappa. Built for rigorous preclinical work, it is supplied in a low-endotoxin format suitable for in vivo use and manufactured in scalable milligram-to-gram quantities for high-throughput and heavy-usage laboratories. Strictly for research use only (RUO), it supports functional assays, receptor-blockade studies, myeloid-cell profiling and in vivo disease modeling with consistent lot-to-lot performance.
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Delivery Time
3-4 weeks
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