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Astegolimab Biosimilar - Research Grade
$710.00 - $6,900.00
Astegolimab Biosimilar - Research Grade
Endotoxin
≤ 1.0 EU/mg as determined by the LAL method
Purity
>90% by SDS-PAGE
Species Reactivity
Human
Target
IL1RL1ï؟½
Concentration
5mg/ml
Isotype
IgG2 - kappa
Host
CHO Cells
Sequence
https://www.imgt.org/mAb-DB/
Buffer
ICH3002
Uniprot
Q01638
Shipping Conditions
Blue ice
Background
ST2 (IL1RL1) is the receptor for the alarmin IL-33 and a key node in type 2 inflammation studied in asthma and allergic disease research. This anti-human IL1RL1 recombinant monoclonal antibody is supplied as an unconjugated, non-therapeutic analog of astegolimab for research use only. Produced to rigorous in vivo standards with low endotoxin, it is manufactured in scalable milligram (mg) to gram (g) quantities to serve bulk and high-throughput laboratories. The reagent is appropriate for receptor-blockade and signalling assays, in vitro functional screening, and in vivo models of allergic and inflammatory disease, delivering dependable results.
Purification Method
This monoclonal antibody was purified using Protein A
Formulation
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Storage
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Applications
Functional Assays
Application Notes
This biosimilar is for research use only (RUO): it is not for diagnostic or therapeutic procedures and cannot be purchased by patients.
Use
Products are for research use only. Not for use in diagnostic or therapeutic procedures.
Delivery Time
3-4 weeks
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